Mushrooms in Cancer Treatment: Brazilian mushroom (Agaricus blazei Murill)

Mushrooms in Cancer Treatment: Brazilian mushroom (Agaricus blazei Murill)

Brazilian mushroom is an edible mushroom native to Brazil and is cultivated widely. A coldwater extract of this mushroom is consumed traditionally in Brazil.

 KA21 is the polysachharide fraction of this mushroom with immune-modulating activity containing a βglucan content of about 12%.

Several studies have shown that beta glucans from these mushrooms can alter cytokine and T- and B-cell activity.

This prompted the view that the mushrooms would not just be applicable to fighting solid tumour cancers, but also in fighting blood cancers where the white cells themselves were in trouble like leukaemia.

Research showed that Agaricus blazei has antiangiogenic (inhibits the formation of new bloodvessels to the tumour) properties.

It inhibits the enzyme aromatase, which is associated with the development of breast cancer. Liver protective and detoxifying properties of Agarics blazei extracts have a detoxifying, blood purifying effect that can help rid the body of dangerous toxins and restore a healthful balance.

In addition, other health benefits including normalized liver function and decreased blood cholesterol levels, were also observed. Mushroom extract also was beneficial in reducing the chemotherapeutic side effects such as nausea, hair loss, loss of appetite, insomnia and other symptoms.

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