Polysaccharides | Bioactive Compounds in Cordycep Militaris

Polysaccharides | Bioactive Compounds in Cordycep Militaris

C. militaris contains large amount of polysaccharides, may be in the range of 3–8% of the total weight.

Polysaccharides attribute for C. militaris various biological activities such as antitumor, antiinfluenza virus, immunopotentiation, hypoglycemic, hypocholesterolemic, and antioxidant effects.

Some polysaccharides such as mannose, galactose, and glucose have been reported present in C. militaris.

Furthermore, other authors have isolated some different polysaccharides. Fhernanda et al., have isolated glucogalactomannan from 5% KOH solution OF dried C. militaris fruiting bodies.

Wang et al., have proposed a method hydrothermal refluxing extraction to extract both cordycepin and polysaccharides in C. militaris.

This method provided the highest yield of cordycepin and polysaccharide extraction.

The extraction was run three times with the raw material-water ratio at 1/10 and each time of 90 minutes.

In addition, Rongmin Yua et al., also have isolated four polysaccharides named as CPS-2, CPS-3, CPS-4 and CPS-5 from the water extract of cultured C. militaris by using ethanol precipitation, deproteination and gel-filtration chromatography methods. 

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