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Shiitake mushroom: Health Benefits


Shiitake mushroom is a fungus. An extract made from this mushroom is used as medicine.


Shiitake mushroom is used for boosting the immune system, HIV/AIDS, lowering blood cholesterol levels, hardening of the arteries, diabetes, eczema, colds and flu, treating prostate or breast cancer, and as an anti-aging agent. It is also used for hepatitis B, herpes, high blood pressure, and stomach ache.


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Shiitake mushroom is used in a mouth rinse for dental plaque.



Shiitake mushroom is also eaten as food.



How does it work?

Shiitake mushroom contains chemicals that might help lower cholesterol levels. It also contains very small amounts of a chemical that seems to keep tumors from getting bigger. This chemical might also stimulate the immune system.

Uses & Effectiveness?

Possibly Ineffective for

  • Dental plaque. Rinsing with liquid containing shiitake mushroom does not seem to reduce plaque (94250).

Insufficient Evidence for

  • Prostate cancer. Early research suggests that shiitake mushroom does not prevent prostate cancer from becoming worse.
  • High cholesterol.
  • High blood pressure.
  • Diabetes.
  • Cold and flu.
  • Other conditions.
More evidence is needed to rate the effectiveness of shiitake mushroom for these uses.

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Paul Stamets

“Of all mushrooms commonly consumed, oyster mushrooms stand out as exceptional allies for improving human and environmental health. These mushrooms enjoy a terrific reputation as the easiest to cultivate, richly nutritious and medicinally supportive.”